Researchers have developed an innovative immunotoxin (a fusion protein called GrB-Fc-KS49) designed to target epithelial membrane protein-2 (EMP2), a biomarker overexpressed in more than 75% of breast ...

In this issue, Thepen and colleagues 1 have taken a more direct approach, targeting the macrophage itself for local apoptotic elimination, using an engineered immunotoxin. Taking advantage of the ...