This important study explores the conserved role of IgM in both systemic and mucosal antiviral immunity in teleosts, challenging established views on the differential roles of IgT and IgM. The ...

“Monoclonal antibodies are our core competence,” said ... “ADLib is a robust and simple method incorporating selection, full-length IgG expression, de novo humanisation, and affinity ...

Monoclonal antibodies directed against human FcRn and ... Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells.

Johnson & Johnson has unveiled groundbreaking findings on nipocalimab, an investigational FcRn blocker, in a recent ...

There are five main types (isotypes) of antibodies, each with distinct structures and functions: IgG, IgM, IgA, IgE, and IgD. Illustration of the five major antibody (immunoglobulin) types ...

The human EphA3 gene was discovered in a pre-B acute lymphoblastic leukemia (pre-B-ALL) using the EphA3-specific monoclonal antibody (mAb ... 488 goat anti-human IgG (A-11013; Life Technologies ...

IgA nephropathy (IgAN) is an autoimmune kidney disease driven by immune cells that express a protein called CD38 on their surface. A recent Phase 2 trial revealed that felzartamab, ...

FMC63, an IgG2a mouse monoclonal antibody, targets CD19. To date, a majority of the reported CART19 trials include the anti-CD19 scFv extracted from FMC63, such as both the FDA-approved CARs ...

This phenomenon prolongs IgG circulation time and antibody response ... a molecular biologist from Liverpool School of Tropical Medicine who was not involved in the study, believes that acid-switched ...

HOUSE, Pa. - Johnson & Johnson (NYSE: NYSE:JNJ) has released new data on nipocalimab, an investigational drug with potential to treat diseases driven by immunoglobulin G (IgG) antibodies. Published in ...