Use of GP IIb/IIIa inhibition in these patients, particularly in combination with thrombolytic therapy or during "rescue" PCI, should be undertaken with caution.

These drugs include abciximab, eptifibatide and tirofiban. Glycoprotein IIb/IIIa inhibitors very strongly inhibit platelet function by blocking fibrinogen binding to the activated glycoprotein IIb ...