or IBD. “The researchers synthesized several compounds containing common secondary bile acids and compared their effects in a mouse model of acute colitis. They found that an orally administered ...

Of the two well-known rodent models of human type 1 diabetes (the non-obese diabetic mouse and the BioBreeding ... deafness and inflammatory bowel disease). The strain's robust breeding ...

to stop inflammation from developing in a mouse model of intestinal bowel disorder (IBD). 1 It is nice to deliver drugs where you exactly want them, which is the gut in the case of IBD and ...

Stressed IBD mouse models showed increased inflammation compared to IBD mouse models without stress. “There are different pathways that can propagate the stress response into the guts,” Schneider ...

Richie is first author of an article titled, "Limitation of amino acid availability by bacterial populations during enhanced colitis in IBD mouse model," published in mSystems. Measuring microbial ...

Figure 1: Representative H&E sections of intestinal tissue from an IBD mouse model without drug treatment showing a high degree of inflammatory cell activity (left) and with TRE-515 treatment ...

Presentation Details: Poster Title: First-in-Class Clinical Stage Deoxycytidine Kinase Inhibitor TRE-515 Blocks Inflammatory Bowel Disease in an Adoptive CD4 Cell Transfer Mouse Model Authors ...

Figure 1: Representative H&E sections of intestinal tissue from an IBD mouse model without drug treatment showing a high degree of inflammatory cell activity (left) and with TRE-515 treatment with ...

Representative H&E sections of intestinal tissue from an IBD mouse model without drug treatment showing a high degree of inflammatory cell activity (left) and with TRE-515 treatment with significantly ...