or IBD. “The researchers synthesized several compounds containing common secondary bile acids and compared their effects in a mouse model of acute colitis. They found that an orally administered ...

We used PROT 3 EcT to deliver nanobodies that bind to and neutralize tumor necrosis factor alpha (TNF-?) to stop inflammation from developing in a mouse model of intestinal bowel disorder (IBD). 1 It ...

Figure 1: Representative H&E sections of intestinal tissue from an IBD mouse model without drug treatment showing a high degree of inflammatory cell activity (left) and with TRE-515 treatment ...

Richie is first author of an article titled, "Limitation of amino acid availability by bacterial populations during enhanced ...

Presentation Details: Poster Title: First-in-Class Clinical Stage Deoxycytidine Kinase Inhibitor TRE-515 Blocks Inflammatory Bowel Disease in an Adoptive CD4 Cell Transfer Mouse Model Authors ...

Representative H&E sections of intestinal tissue from an IBD mouse model without drug treatment showing a high degree of inflammatory cell activity (left) and with TRE-515 treatment with significantly ...

Figure 1: Representative H&E sections of intestinal tissue from an IBD mouse model without drug treatment showing a high degree of inflammatory cell activity (left) and with TRE-515 treatment with ...