The new compound is an inhibitor of soluble epoxide hydrolase (sEH), an enzyme involved in the regulation of several ...

A research team have recently published their article, "Rationally designed pooled CRISPRi-seq uncovers an inhibitor of ...

Researchers from the University of Barcelona have developed a compound that inhibits soluble epoxide hydrolase (sEH), showing ...

Hydrolases are enzymes that catalyze the cleavage of a covalent bond using water. Types of hydrolase include esterases, such as phosphatases, that act on ester bonds, and proteases or peptidases ...

Tenvie Therapeutics Inc. has divulged NAD(+) hydrolase SARM1 (SAMD2; MyD88-5) inhibitors reported to be useful for the treatment of glaucoma, spinal cord injury, multiple sclerosis, Niemann-Pick ...

The following is a summary of “A high-performance core laboratory GFAP/UCH-L1 test for the prediction of intracranial injury after mild traumatic brain injury,” published in the March 2025 issue of ...

Les glycosidases dont le produit a, pour son carbone anomérique, une configuration absolue identique de celle maintenue dans le substrat, ont un mécanisme rétenteur (ou conservateur). Typiquement ces ...

Arrepath Inc. has disclosed UDP-2,3-diacylglucosamine hydrolase (LpxH; bacterial) inhibitors reported to be useful for the treatment of gram-negative bacterial infections.