directed against human eosinophils. The heavy and light chains of that fully human anti-human eosinophil mAb were delivered via an adeno-associated virus (AAV)-based gene therapy to ...

In the course of the ALS development program, however, dexpramipexole was observed to produce a significant and targeted depletion of eosinophils in the blood of ALS patients 4. Eosinophils are ...