Statins lower plasma cholesterol by upregulating LDL receptor gene expression and are consequently relatively ineffective in homozygous familial hypercholesterolemia (HoFH). The standard treatment ...

Consequently, a test cross can help determine whether a dominant phenotype is homozygous or heterozygous for a specific allele. Diploid organisms, like humans, have two alleles at each genetic ...

Individuals A and B both have brown eyes, even though A is heterozygous and B is homozygous (dominant). Only people with a homozygous recessive genotype can have blue eyes as shown by individual C.

Some experts believe that having two mutations (homozygous) may lead to more serious problems. There are two variants, or forms, of mutations that can occur on the MTHFR gene. The specific ...