How is all of that DNA packaged so tightly into chromosomes and squeezed into a tiny nucleus? Histones are a family of small, positively charged proteins termed H1, H2A, H2B, H3, and H4 (Van Holde ...

Targeted de novo methylation during development involves SET domain-containing proteins that are capable of specifically methylating histones as well as recruiting DNA methyltransferases.

The team thought it might be a good candidate for finding histones because the bacterium changes size throughout its lifecycle and thus would need to carefully time DNA compression and unwinding. As a ...

We've now zoomed in enough to see portions of the DNA strand. The DNA is wrapped around histones -- protein structures that are sometimes depicted as discs. Histones carry a slight positive charge ...

Histones proteins were selected early in evolution to transform DNA into chromatin filaments formed by many nucleosomes. The ...

The study, published in the prestigious journal EMBO Journal, reveals why some tumors escape the immune system, and offers a ...

Science never ceases to amaze us, and one of the most mind-blowing facts about the human body is the sheer length of our DNA. If you unraveled all the DNA in your body and laid it out in a straight ...

Studies have also have tapped into the nature of DNA’s primary packing material: protein spools called histones around which genomes wind to form nucleosomes. Nucleosomes, which are often compared to ...

The mechanism of a peculiar type of heterochromatin, used by embryonic stem cells to silence 'parasitic' DNA-elements within the context of their highly dynamic pluripotent chromatin. Disclaimer ...