In vertebrates this organelle is a subset of Cajal bodies, whereas in Drosophila melanogaster it comprises a distinct structure called the histone locus body. Recent studies suggest an unexpected ...

Here, we focus on how chromatin modifications and structure are propagated; we first summarize how replication occurs and then consider models of histone segregation. Importantly, the initiation ...

Berger and her collaborators chemically altered histone structure in the brains of young majors using small-molecule inhibitors of histone deacetylases or small interfering RNAs (siRNAs). Newly ...

With this strategy, he discovered over 400 bacterial proteins that contain a signature 3D histone structure called a histone fold, suggesting histones could be scattered across many bacterial species.