Although considerable progress has been made towards understanding the dynamic landscape of histone-methylation regulation, the biological functions of these newly found demethylases are just ...

Discover how histone modifications unlock secrets of human aging, rivaling the precision of DNA methylation in decoding biological age. In a recent study published in the journal Science Advances ...

Aging cells with weakened gene regulation spuriously transcribe RNAs ... These fragments can then be sequestered for analysis using histone-specific antibodies. Sen and her colleagues studied ...

Some twenty years ago, Massachusetts Institute of Technology biologist Lenny Guarente began studying aging by timing the lifespan of various yeast strains ... as some studies had suggested and which ...