The histone code can be viewed from both a single PTM ... PTM: Post-translational modification. Middle-down electron transfer dissociation mass spectrum of the [M+6H] 6+ 1–23 H4 peptide ion ...

Histone post-translational modifications (PTMs ... PTMs simultaneously occurring on the same molecule (the histone code). Future proteomics research is heading towards interrogation of histones ...

These observations strongly suggested that two major classes of histone modification might act in opposition to help specify a gene regulatory code for the β-globin gene. That is, transcriptional ...

To analyze the success of the experiment, carry out amplification of 1–2 μl of the diluted DNA as a template, using PCR primer pairs that amplify sequences for which the histone modification ...

This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...