The samples included seven histone modifications: histone H3 lysine 4 trimethylation (H3K4me3 ... Histone-based predictors were compared to DNA methylation-based predictors, with the study ...

Recent research has expanded our understanding of lysine methylation beyond its traditional focus on histone proteins, revealing its importance in various non-histone substrates and cellular ...

Histone deacetylation and other modifications, particularly the methylation of lysine 9 within histone H3 (H3-K9) residues located in the histone tails, cause chromatin condensation and block ...

Researchers have previously found that the methylation of one particular location, lysine-4, on histone H3, is closely correlated with turning genes "on." Knowing that this relationship exists ...

In a groundbreaking study led by Dr. Ying Chen and her team from Ruijin Hospital, Shanghai Jiao Tong University School of ...

Dopamine, serotonin, and histamine carry messages between neurons. They can also influence circadian gene expression ...

“Generally, methylation at the promoters of genes is associated ... and then you take an antibody for [histone 3 lysine 27 trimethylation] or some other kind of protein feature, and then you enrich ...

Discover how histone modifications unlock secrets of human aging, rivaling the precision of DNA methylation in decoding biological age. In a recent study published in the journal Science Advances ...