providing they can enter the CNS. Researchers have proposed a range of solutions, and receptor-mediated transport (RMT) is now widely regarded as “one of the most efficient and safest routes to ...

Receptor cells detect a change in the environment (a stimulus) and start electrical signals along neurons. These move towards the central nervous system (CNS). The CNS is the brain and spinal cord.

TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008. Schematic of TNF inhibitors and their mode of action. Receptor ...

IL-17A signals through its receptor, IL-17RA, which is expressed in many peripheral tissues; however, expression of IL-17RA in the central nervous system (CNS) and its role in CNS inflammation are ...

Receptor in the skin detects a stimulus (the change in temperature). Sensory neuron sends electrical impulses to a relay neuron, which is located in the spinal cord of the CNS. Relay neurons ...