真实世界研究揭示HER2低表达并非独立预后因素,而是与临床病理特征相关。乳腺癌是全球女性最常见的恶性肿瘤之一。近年来,HER2低表达(HER2-low)乳腺癌作为一种新的治疗亚型备受关注。HER2-low乳腺癌是指HER2免疫组化(IHC)表达为1+ ...
*仅供医学专业人士阅读参考研究揭示了HER2低表达与高复发评分的显著关联,为精准诊疗提供临床新证据。近年来,在乳腺癌的复杂谱系中,HER2表达水平的异质性为临床治疗决策带来了挑战。尤其是HER2低表达(HER2-low)乳腺癌患者,由于其对新型抗体药 ...
3月21日,吉利德科学宣布,全球首个获批的靶向Trop-2的抗体偶联药物(ADC)戈沙妥珠单抗(商品名:拓达维)获得中国国家药品监督管理局 (NMPA)批准,用于治疗既往接受过内分泌治疗且在转移性疾病阶段接受过至少二种其他系统性治疗的不可切除局部晚期或转移性的激素受体 (HR)阳性、人类表皮生长因子受体2 ...
尤其是HER2低表达(HER2-low)乳腺癌患者,由于其对新型抗体药物偶联物(ADC)显示出临床获益,这一亚群也越来越受到关注。尽管HER2-low乳腺癌的 ...
随着乳腺癌HER2三分类新时代的到来,HER2精准检测的重要性日益显著。而病理学家对HER2 IHC评分的判读具有主观性,当前亟需一种标准化的方法来确保 ...
Patients with recurrent/metastatic HER2-positive breast cancer experienced durable response and manageable safety from ...
REVEAL GENOMICS ®, a pioneering Barcelona-based biotech company dedicated to advancing precision oncology, is proud to announce the publication of a groundbreaking study demonstrating the clinical ...
Seth Wander, MD, PhD, discusses the significance of ESR1 mutations in patients with hormone receptor–positive, HER2-negative ...
A real-world study showed HER2DX guided treatment changes in approximately 48% of HER2-positive breast cancer cases.
Data presented at European Molecular Imaging Meeting (EMIM 2025) for imaging with 68Ga-RAD202 confirms specific accumulation in the tumor, ...