Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells ... which leads to toxic stress that can disrupt cell function." Dr. André Catic, corresponding author ...

More information: Sho Kubota et al, Chromatin modifier Hmga2 promotes adult hematopoietic stem cell function and blood ...

Hematopoietic stem cells (HSCs ... We have also discovered that infection can be a driver of Dnmt3a-loss of function clonal hematopoiesis, and defined the transcriptional and epigenetic mechanisms ...

We are also studying the role of epigenetic modifications, such as DNA methylation, on hematopoietic stem cell (HSC) function and biology. In particular, the lab is investigating the role of DNA ...

Eight patients are alive with normal marrow cellularity and function when assessed at 1 ... fibronectin CH-296 was associated with prompt hematopoietic recovery and no adverse events.

The Metachromatic Leukodystrophy Initiative (MLDi) critically responds to the findings of Zhang et al. on lentivirus-modified ...