Hematopoietic stem cells (HSCs) are the precursors of all cells of the peripheral ... We have also discovered that infection can be a driver of Dnmt3a-loss of function clonal hematopoiesis, and ...

We are also studying the role of epigenetic modifications, such as DNA methylation, on hematopoietic stem cell (HSC) function and biology. In particular, the lab is investigating the role of DNA ...

Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells ... which leads to toxic stress that can disrupt cell function." Dr. André Catic, corresponding author ...

This study confirms the immune-boosting and hematopoietic-promoting effects of ribonucleic acid for injection II, which has a ...

Featured data showcase the transformative potential of HSC gene therapy to enable cross-correction and restore enzymatic ...

The Metachromatic Leukodystrophy Initiative (MLDi) critically responds to the findings of Zhang et al. on lentivirus-modified ...

Fanconi anemia (FA) is a rare genetic disorder characterized by defective DNA repair, leading to hematopoietic stem cell (HSC) dysfunction and bone marrow failure. Replication stress, which ...