Bioinformatics revealed two putative granzyme B cleavage sites in HSV-1 immediate early protein ICP4, which is required to switch transcription from latent to lytic genes. In a proteolysis assay ...
All available evidence indicates that PML-NB proteins associate with HSV-1 and HCMV genomes at the very beginning of both lytic and quiescent infections, and implies that this association is also ...
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