HMG-CoA reductase inhibitors may impair the biosynthesis ot nonsterol isoprenes in a fashion analogous to that observed in mevalonic aciduria ...

Abstract and Introduction Pathophysiology and Implications of Atherosclerosis Emerging Role of Statins Discussion References Current studies have questioned the relationship between CRP and LDL ...

HMG-CoA reductase inhibitors, commonly referred to as statins, are the cornerstone of pharmacologic reduction of elevated low-density lipoprotein cholesterol. LDL-C is the main contributor to ...

On the basis of these facts, I speculated that a cholesterol-synthesis inhibitor, particularly a HMG-CoA reductase inhibitor, would be an effective cholesterol-lowering agent. In the 1960s ...

In patients with hypercholesterolemia, ezetimibe added to ongoing HMG-CoA reductase inhibitor therapy significantly lowered total cholesterol, LDL-C, apolipoprotein B, and triglycerides and ...

Do not take two doses at the same time. Simvastatin and atorvastatin are cholesterol-lowering medications classified as HMG-CoA reductase inhibitors. They lower cholesterol levels by preventing ...

aldosterone antagonists and HMG-CoA reductase inhibitors. Early antithrombotic administration at the time of STEMI diagnosis consists of non-enteric-coated aspirin 162 mg to 325 mg (unless ...

These medications work by inhibiting an enzyme called HMG-CoA reductase, which plays a key ... heart disease and improving heart function. ACE inhibitors (Angiotensin-Converting Enzyme inhibitors ...

They work by inhibiting an enzyme in the liver called HMG-CoA reductase and by inhibiting ... that same effect of causing liver damage. PCSK9 inhibitors are a new class of medications that may ...

Concomitant cisapride, pimozide, ergots, lomitapide, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). Concomitant colchicine (in renal or hepatic ...