Abstract and Introduction Pathophysiology and Implications of Atherosclerosis Emerging Role of Statins Discussion References Current studies have questioned the relationship between CRP and LDL ...

HMG-CoA reductase inhibitors may impair the biosynthesis ot nonsterol isoprenes in a fashion analogous to that observed in mevalonic aciduria ...

HMG-CoA reductase inhibitors, commonly referred to as statins, are the cornerstone of pharmacologic reduction of elevated low-density lipoprotein cholesterol. LDL-C is the main contributor to ...

On the basis of these facts, I speculated that a cholesterol-synthesis inhibitor, particularly a HMG-CoA reductase inhibitor, would be an effective cholesterol-lowering agent. In the 1960s ...

HMG-CoA reductase inhibitors, better known as statins, are medications taken to lower cholesterol levels. Examples of statins include Lipitor (atorvastatin), lovastatin, and Zocor (simvastatin).

Teemu Kantola, Effects of itraconazole and some other CYP3A4 inhibitors on the pharmacokinetics of HMG-CoA reductase inhibitors. Vilja Palkama, Studies on drug interactions between CYP3A4 inhibitors ...

Pravigard PAC (buffered aspirin and pravastatin sodium; Bristol-Myers Squibb, Princeton, NJ) is a copackaging of; Bristol-Myers Squibb, Princeton, NJ) is a copackaging of Pravachol and buffered ...

aldosterone antagonists and HMG-CoA reductase inhibitors. Early antithrombotic administration at the time of STEMI diagnosis consists of non-enteric-coated aspirin 162 mg to 325 mg (unless ...

Medically reviewed by Femi Aremu, PharmD Zocor (simvastatin) and Lipitor (atorvastatin) are both statin drugs, which are medications used to lower cholesterol levels in the blood. Statins primarily ...

They work by inhibiting an enzyme in the liver called HMG-CoA reductase and by inhibiting ... that same effect of causing liver damage. PCSK9 inhibitors are a new class of medications that may ...

These medications work by inhibiting an enzyme called HMG-CoA reductase, which plays a key ... heart disease and improving heart function. ACE inhibitors (Angiotensin-Converting Enzyme inhibitors ...

Concomitant cisapride, pimozide, ergots, lomitapide, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). Concomitant colchicine (in renal or hepatic ...