3-Hydroxy-3-methylglutaryl (HMG)-CoA reductase, an enzyme that catalyzes the conversion of HMG-CoA into mevalonate, proved to be the rate-controlling enzyme in cholesterol synthesis. On the basis ...

The CV benefit of statins can be partly explained by their ability to inhibit of HMG-CoA reductase, which subsequently lowers cholesterol and decreases the formation of mevalonate. However ...

HMG-CoA reductase inhibitors, commonly referred to as statins, are the cornerstone of pharmacologic reduction of elevated low-density lipoprotein cholesterol. LDL-C is the main contributor to ...

HMG-CoA reductase inhibitors, better known as statins, are medications taken to lower cholesterol levels. Examples of statins include Lipitor (atorvastatin), lovastatin, and Zocor (simvastatin).

Statins primarily work by inhibiting the enzyme HMG-CoA reductase, a protein that helps make cholesterol in your body. Zocor and Lipitor are both effective at lowering low-density lipoprotein (LDL ...

These medications work by inhibiting an enzyme called HMG-CoA reductase, which plays a key role in cholesterol production within the liver. By decreasing cholesterol levels, particularly low ...

They work by inhibiting an enzyme in the liver called HMG-CoA reductase and by inhibiting that enzyme, you’ll actually prevent the liver from producing cholesterol. Jyoti Sharma continued ...

aldosterone antagonists and HMG-CoA reductase inhibitors. Early antithrombotic administration at the time of STEMI diagnosis consists of non-enteric-coated aspirin 162 mg to 325 mg (unless ...