One of the key findings was the discovery of previously unrecognized elements in HIV-1 RNA called upstream open reading frames (uORFs) and internal open reading frames (iORFs). These "hidden gene ...

HIV-1 gene expression and capsid assembly. Here, the authors present a comprehensive review of the molecular mechanisms involved in iron- and oxygen-mediated regulation of HIV-1 replication.

They graphically represent the life cycle of HIV-1, from the initial binding of the ... spark the formation of new viral RNA strands (Viral Gene Transfer), and finally to the creation and ...

(Manuscript submitted). Sung TL, Rice AP. PLoS Pathog. 2009 Jan;5(1):e1000263. Epub 2009 Jan 16. miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears ...

This gene-editing tool had won the Nobel Prize in 2020. "Striving for an inclusive ‘HIV cure for all’ that can inactivate ...