“This study reveals that this enzyme [nSMase2] is such an enzyme that the virus has evidently hijacked to use in its replication strategy.” Previous research suggested that HIV infection increased the ...

Once HIV has bound to CD4, it activates other proteins on the surface of the human cell known as CCR5 and CXCR4 in order to complete its fusion with the cell. Once fusion has occurred, the inside of ...

in particular hepatitis C virus (HCV). Although HCV is fundamentally different to HIV, several classes of drugs targeting viral enzymes — in this case HCV RNA replicase and HCV serine protease ...

Methods to improve the distribution of enzymes that are injected or expressed ... the protein transduction domain (PTD) from HIV Tat, could improve the distribution of cytoplasmic reporter ...

“So then that's in your body, and it's making more virus in your body.” The first HIV drug, which came out in 1987, blocked nucleoside reverse transcriptase, an enzyme HIV uses to replicat ...

People with HIV have a virus that spreads in their body and damages ... Sunlenca is also a moderate CYP3A enzyme inhibitor and may raise the chance of side effects from certain medicines broken ...

Integrase inhibitors stop the virus from inserting itself into the DNA of human cells. Protease inhibitors (PIs) block the activity of the protease enzyme, which HIV uses to break up large ...

A technique invented by the lab, known as Electron Microscopy-Based Polyclonal Epitope Mapping (EMPEM), lets the researchers see exactly where on the HIV virus antibodies bind. When they carried ...

The cell that the vector later invades will then produce proteins created by the virus. The vectors and copied genes have been treated with restriction enzymes ... a naked-DNA HIV vaccine.

On a nitty-gritty biological level, EBC-46 binds to a key enzyme known as protein kinase C ... Wender and colleagues have ...

EBC-46 is known to bind with key enzymes known as protein ... across various medical contexts, including HIV. In this case, the need for effective virus eradicating strategies is of primary ...

The Alzheimer's-linked gene, called APP, undergoes this transformation using the same enzyme -- reverse ... drug "cocktail" that HIV-positive people use to suppress the virus.