The occurrence of CXCR4-using HIV-1 variants is generally indicative of an advanced stage of infection and associated with accelerated disease progression 7,8. Consequently, one key goal of ...

Many of these would also be observed in worrying variants, including the Alpha variant that sent case counts rocketing and ...

Data from our group have demonstrated that some, but not all, low-level resistant variants can lead to virologic failure as other active agents in a regimen (with different genetic barriers) may ...

There are biological and clinical questions facing the field of HIV genotyping such as the need to better define the level of sensitivity required to detect drug-resistant variants, how different ...

By focusing on these conserved sections, the approach aims to provide a broad-spectrum therapy capable of combating multiple HIV variants effectively. Their experiments showed outstanding ...

“The discovery of this novel HIV-1 lineage highlights the continuing need to monitor closely for the emergence of new HIV variants. This demonstrates that HIV evolution is an ongoing process. The ...

They say this will help them provide a broad-spectrum therapy capable of combating multiple HIV variants effectively, but stressed their work provides proof of a concept, and will not become a ...

A main obstacle to an HIV cure is that viral DNA integrates into the chromosomes of memory T cells (blue), which evade ...

A group of leading African researchers trying to develop effective vaccines against HIV is trying to figure out how to ...

In a moment of both triumph and uncertainty, South Africa's scientific community has unveiled encouraging results from a landmark HIV cure trial conducted in Durban, KwaZulu-Natal. The University of ...

A Stanford-led team has found two antibodies that can work together to defeat all SARS-CoV-2 variants. More research is needed, but the approach could help in the development of treatments to keep ...

Her research in sex workers highlighted the role that other infections play in shaping the number of HIV variants that hop from one person to another. Her team also studied how the immune system ...