感染性病毒的产生：研究人员构建出缺乏 5'-LTR 的线性 HIV DNA（1-LTR HIV ），这种线性形式转录无活性，但经环化后成为有转录活性的 1-LTR 环形 DNA。将其转染到缺乏 CD4 的 HeLa-tat 细胞（CD4 阴性）和 Jurkat T 细胞（CD4 阳性）中，在 HeLa-tat 细胞中只产生 1-LTR 环形形式 ...

The Rice laboratory studies how gene expression is regulated in HIV - the virus that causes AIDS. The major focus of our research is on the HIV Tat protein, which is essential for HIV transcription, ...

which forms the central conical core of HIV that encapsulates the viral accessory and regulatory proteins (Vif, Vpr, Vpu, Nef, Tat and Rev), the Pol proteins (protease (Pro), reverse transcriptase ...