Early steps of infection by HIV-1 involve entry of the viral core into cells, reverse transcription to form the linear viral DNA, and integration of that DNA into a chromosome of the host.

A recent study has identified a triple stranded HIV cDNA intermediate of reverse transcription, or a ‘central DNA flap,’ as a component of HIV nuclear import. The retroviral replication cycle ...

Drug-resistance amino acids known in HIV-1 [36] are shown in bold ... they function as a chain terminator and inhibit reverse transcription. NRTI-resistance mutations & their mechanism of drug ...

After the HIV virus releases its genetic material into a host cell, reverse transcriptase converts the viral RNA into DNA, a process known as ‘reverse transcription’. NRTIs disrupt the construction of ...

Human immunodeficiency virus (HIV) remains a global health challenge ... paper-based sample preparation with real-time ...