have pursued the development of nucleoside and nonnucleoside drugs targeting HCV polymerase, in the knowledge that intervening at a similar point in the HIV lifecycle has proven successful in the ...

Recent studies have highlighted the potential of dual inhibitors that target both the polymerase and RNase H activities of HIV-1 reverse transcriptase. These dual inhibitors are designed to ...

Using a technique called PCR, which stands for polymerase chain reaction ... You have just produced a naked-DNA HIV vaccine. Trials for a genetic vaccine that may protect against AIDS began ...

The p66 subunit of HIV-1 reverse transcriptase has two domains: a DNA polymerase domain (with fingers, palm, thumb and connection subdomains) and an RNase H domain. The four subdomains and the ...

Experiments in cells showe how changes in the viral polymerase -- a protein involved in viral replication -- can alter the virus's ability to make copies of itself and infect cells. Further ...

Post birth care After the birth of the child, the baby should be tested for HIV by polymerase chain reaction (PCR) test at birth, 4–6 weeks of life and when the breastfeeding is discontinued.