Would you consider them living or nonliving? Let’s look closely at the life cycle of the human immunodeficiency virus (HIV) – the virus that causes AIDS – to find out. This transmission electron ...

or a ‘central DNA flap,’ as a component of HIV nuclear import. The retroviral replication cycle requires that retroviral nucleic acids integrate into the cellular DNA of the host cell.

This image shows the replication cycle of HIV/SIV. The virus replicates in the body's own CD4+ T helper cells. In doing so, it introduces its own genetic information into the DNA of the host cell.

They graphically represent the life cycle of HIV-1, from the initial binding of the viral particle onto a host cell (Viral Entry), through insinuation into the host cell's nucleus to spark the ...

HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.

despite their ability to resist full infection by HIV, respond to the presence of viral DNA by sacrificing themselves via pyroptosis—a highly inflammatory form of cell death that lures more CD4 T ...

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a ...

Without the means to enter a cell, HIV cannot replicate ... with the HIV capsid at various stages of the viral life cycle. Fixed-dose combination drugs reduce the daily pill burden a person ...

Medically reviewed by Michael Menna, DO HAART is the acronym for "highly active antiretroviral therapy" used to treat HIV ...

[2] The papers show that targeting nSMase2 in a cell that is making HIV-1 changes the lipid composition of the virus particle ... “This enzyme is one foot in the door to better understanding the viral ...