Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will ...

For some HIV vaccines, repetitive immunizations lead to a chain reaction of antibody production against immune complexes ...

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby ...

Repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus ...

For example, an antibody that can recognise an antigen on the Salmonella bacterium will not recognise an antigen on the HIV virus. Scientists discovered that we can make antibodies to bind to ...

spurring the production of new antibodies, including some that bind to existing immune complexes on the virus' surface. In a series of follow-up experiments on HIV-vaccinated animals, Brown ...

N6 is a newly discovered antibody at NIAID. It has evolved a unique mode of binding that depends less on a variable area of the HIV envelope known as the V5 region and focuses more on conserved ...

Their innovative approach focused on increasing the frequency of specific mutations that the immunogen could trigger, ultimately leading to better antibody production. The team validated its ...

Get Instant Summarized Text (Gist) An HIV vaccine candidate has been developed that effectively guides immune cells to evolve into broadly neutralizing antibodies (bnAbs). In mouse studies, the ...