基因转录异常已被确认为肿瘤的重要特征之一，由此引发的基因表达失调可导致肿瘤的发生和恶性进展。转录调控与染色质结构密切相关。核小体是染色质的基本组成单位，由147个DNA碱基对环绕在由核心组蛋白H2A、H2B、H3和H4 ...

Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4. The chain of nucleosomes is then wrapped into a 30 nm spiral called a solenoid, where additional ...

Japan’s space agency announced plans for seven or more lift-offs annually of its flagship H3 rocket from the Kagoshima complex in Kyushu. The science ministry and the Japan Aerospace Exploration ...

Setd2 is instrumental in the trimethylation of histone H3 lysine 36 (H3K36me3), a modification that influences gene expression and has been implicated in various cancers and developmental disorders.