Discover how the brain's most abundant neurotransmitter, glutamate, is revolutionizing psychiatry and offering new hope for ...

Scientists used advanced cryo-EM imaging to reveal how glutamate activates brain receptors, paving the way for new ...

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most ...

Researchers used advanced cryo-electron microscopy to capture atomic-level images of how glutamate, a key neurotransmitter, ...

When glutamate signaling goes awry, either too much or too little, mental health can suffer profoundly. Recent advances in neuroscience are revealing how glutamate dysregulation underlies ...

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most ...

The metabotropic glutamate receptors (mGluRs ... we investigated whether these receptors modulate nociceptive signaling, and found that agonist-induced activation of peripheral group I mGluRs ...

The company, launched with help from ex-Novartis executives, is targeting glutamate signaling in the brain to help treat alcohol- and cocaine-use disorders, among other indications.

Here, we explored how NMDARs signal in tLTD. We found that, regardless of frequency, L5 PC→PC tLTD relies on the non-ionotropic preNMDAR signaling pathway mediated by JNK2, which helps to resolve the ...

In their latest study, researchers found that these Lepr neurons communicate using two different chemical signals: glutamate, which excites neurons ... Münzberg, professor in Pennington Biomedical's ...

Immediately after this, the receptors were flash frozen and analyzed with cryoEM to get a snapshot of the AMPA receptors bound to the major signaling molecule, glutamate. After assembling more ...