We have investigated the role of mitochondrial calcium buffering in excitotoxic cell death. Glutamate acts at NMDA receptors in cultured rat forebrain neurons to increase the intracellular free ...

He is characterizing modulators of glutamate transporters in conditioned place preference approaches and other non-evoked pain behavior paradigms. Simran Gill is a PhD student in the Pharmacology and ...

Glutamate, the main excitatory neurotransmitter in the central nervous system, is involved in cognitive functions such as learning and memory. Excitatory amino acid transporters (EAATs) present on the ...

Sleep's role to down-scale glutamate, excitatory, frontal cortical synapses is extended to include an up-scaling of metaplastic LTP potential, in recovery from prolonged waking induced saturation of ...

The Synaptic Physiology laboratory directed by CSIC researcher Juan Lerma at the IN has extensively investigated glutamate ...

Surprisingly, however, AMPARs have a low affinity for glutamate, so they anchor themselves ... professor of molecular physiology and biophysics, and Ingo Greger, group leader at the MRC Laboratory ...