Ketamine may work in other ways in the brain, too. Some nerve cells in the brain involved in mood use a chemical called glutamate to communicate with each other. The nerve cells need glutamate ...

The findings point the way to treatment options targeting group 1 metabotropic glutamate receptors. This study is a major step toward the ultimate goal of treating fragile X syndrome (FXS), an ...

Exploring new treatment avenues has become crucial as mental health challenges such as depression and PTSD continue impacting a significant number of individuals globally. Traditional therapies might ...

The Food and Drug Administration (FDA) recently approved the nasal spray Spravato for the treatment of major depression in ...

Most of these neurons use glutamate (a neurotransmitter for signaling), while some use serotonin (important for mood). They found that these IL-1R1-positive neurons are involved in circuits that ...

The U.S. Food and Drug Administration ( FDA) has approved the use of a nasal spray as a standalone treatment for major depressive disorder, offering a new option for those struggling with ...

A ketamine-based nasal spray is officially the first and only standalone therapy available for treatment-resistant depression in the US.