They demonstrated that a reduced expression of PICALM improves insulin sensitivity and glucose transport in fat cells. These ...

Renal glucose reabsorption involves two transporter families: the SGLTs secondary active Na + /D-glucose co-transporters located at the brush border of tubular cells (SGLT2 and SGLT1) and the ...

Beyond its established function of recycling cellular waste, ATG5 prevents the excessive accumulation of glucose transporter 2 (GLUT2) on the cell surface during brain development. This regulation ...

Glucose enters cells via specific transporters (GLUTs) located in the cell membrane. There are several types of GLUTs, varying in their location (tissue specificity) and in their affinity for glucose.

The following is a summary of “Effects of Novel Antidiabetic Agents on Contrast-Associated Acute Kidney Injury in Diabetic Patients Undergoing Percutaneous Coronary Intervention,” published in the ...

Calorie restriction, physical activity and the drug dapagliflozin caused 44% of participants in a small trial to enter diabetes remission Dapagliflozin is a sodium glucose co-transporter 2 (SGLT2) ...

sodium-glucose transporter 2 (SGLT2) inhibitors — these reduce the amount of glucose reabsorbed by the kidneys, meaning that it is excreted in the urine. A meta-analysis, published in the Journal of ...

A thorough examination of modern drugs that target particular receptors and metabolic pathways for glucose and fat metabolism is presented. Recent research has revealed innovative targets and ...

Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from elevated blood glucose levels that stems from the decreased secretion and/or ...