A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene "silencer" that resides in junk DNA is directly sparing people from a ...

A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene ...

Constitutive splicing is where every intron in the primary RNA transcript is removed as transcription progresses along the gene. Alternative splicing is where exon or intron skipping can occur.

Post-mortem examination of a mouse heart shows a clear delineation in blue where TREE gene enhancer sensed and responded to tissue damage of a heart attack. photo - Ken Poss Lab, Duke University ...

Enhancer Biology lab studies gene regulation and genome architecture controlled by transcription factors using genome-wide functional genomics methods. Our aim is to understand enhancer malfunction ...

Because of their closed population stemming from a small number of German immigrants -- about 200 individuals -- the Amish carry unusual concentrations of gene mutations that cause a number of ...