Lipid nanoparticle platform delivers mRNA to the brain
New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier
Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier.
For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the ...
Researchers at the National University of Singapore have reported crossing the blood–brain barrier with help from a modified Lactobacillus plantarum. By delivering an appetite-regulating hormone ...
Get Instant Summarized Text (Gist) The blood-brain barrier, a protective shield for the brain, poses a significant challenge for delivering medications to treat neurological diseases. Recent ...
The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been ...
The Swedish biotech behind a groundbreaking Alzheimer’s treatment is in talks with partners for its new technology that allows drugs to cross the notoriously tricky blood-brain barrier.
The delivery challenge is posed by the blood–brain barrier (BBB), which prevents around 95% of small molecules, and almost all therapeutic biologics, from leaving the bloodstream and entering ...
showing they can cross the blood-brain barrier, and the amounts of the tiny plastic bits inside our bodies appear to be increasing at a rate that reflects the increasing amount of global plastic ...
The Mt. Sinai study could open the door to future therapies for Alzheimer’s, amyotrophic lateral sclerosis, brain cancer, and ...
ABL Bio’s first-in-class bispecific antibodies for Parkinson’s disease combine unprecedented blood–brain barrier penetration with a robust mechanism of action for improved therapeutic efficacy.
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