Protein-protein interactions govern a large number of biological processes. A number of cell surface and nuclear receptors mediate their actions via dimerization. While this has been well ...

As results indicated that the spinal antinociceptive effect of diazepam is mediated predominately by GABA A receptor isoforms containing the α2 and α3 subunits, the authors next tested whether ...

Certain proteins found in the human brain have long been known to be critical to controlling how brain cells communicate with each other. So-called GABAA receptors are proteins that control the flow ...

γ-aminobutyric acid (GABA), whether it be lower levels of GABA or the receptor it binds to. But a study published last week (October 3) in Science Translational Medicine, which zeroed in on GABA ...

A paradigm-shifting study from the Centre for Addiction and Mental Health (CAMH) shows an experimental drug, GL-II-73, has the potential to restore memory and cognitive function in a mouse model of ...