Reduced glutathione or simply glutathione (γ-glutamylcysteinylglycine; GSH) is found in the cytosol of most cells of the body. GSH in the epithelial lining fluid (ELF) of the lower respiratory ...
Ferroptosis was first identified in RAS-mutant cancer cells exposed to erastin and related compounds, which inhibit the cystine/glutamate antiporter (system Xc-) and impair GSH synthesis.
Because the subtraction was assumed to be perfect, only those metabolites with resonances close to 1.9 ppm were included in the simulations: GABA, glutamate (Glu), glutamine (Gln), glutathione (GSH), ...