G Protein-Coupled Receptors (GPCRs) in advancing GPCR-targeted therapies, including the use of agonists, antagonists, biased ...

However, these classical models of receptor/G protein coupling may be oversimplified since a number of studies report not only the presence but also a role for GPCR multimers in modulating ...

此外，药用动物来源的其他成分如牛磺熊去氧胆酸可通过靶向 G 蛋白偶联胆汁酸受体 1（TGR5）发挥抗炎和舒张血管作用。 基于不同机制的 GPCR 配体筛选方法 基于配体结合的筛选：传统药物通过直接或间接与多种 GPCR 亚型相互作用发挥作用。配体筛选是 GPCR 药物 ...

Studies Kaposi’s sarcoma herpesvirus (KSHV) G protein-coupled receptor (GPCR) contribution to metabolic regulation, trafficking and signaling, using tissue culture models and molecular biology ...

Alphabet subsidiary and precision health company Verily recently announced a breakthrough in its AI drug discovery GPCR research collaboration ... options against G protein-coupled receptors ...

Adhesion G protein-coupled receptors (GPCRs ... "Our new numbering system is an important step forward in GPCR research. It will facilitate basic research and encourage comparative studies.

Maxion Therapeutics Raises $72 million (£58 million) in an Oversubscribed Series A Financing to Advance its KnotBody® Pipeline and Platform Financing led by General Catalyst with additional investment ...

Maxion Therapeutics Ltd. has raised $72 million (£58 million) in a series A financing to support its development of antibody-based Knotbody drugs for ion channel- and G protein-coupled receptor (GPCR) ...

Feb. 26, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that Jeffrey ...