At the interface between these circulating factors and insulin/glucagon secretion are GPCRs, which in islets mediate the effects of many of the circulating factors, such as glucagon-like peptide-1 ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

New numbering system facilitates comparability of protein domains Researchers analyze models using AI Date: January 28, 2025 Source: Universität Leipzig Summary: Adhesion GPCRs are a group of ...

Get Instant Summarized Text (Gist) A new numbering system for the GAIN domain of adhesion G protein-coupled receptors (GPCRs) has been developed to standardize protein domain comparison, enhancing ...