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生物通
13 天
硫化氢诱导应激颗粒形成的分子机制及其对细胞保护作用的研究
为探究高浓度硫化氢(H 2 S)对细胞的影响,研究人员利用人支气管 BEAS-2B 和稳定转染 GFP 标记的 G3BP1 的 CHO 细胞开展研究。结果发现 H 2 S 可经 eIF2α 磷酸化诱导应激颗粒(SGs)形成和翻译抑制,保护细胞免受死亡,为相关研究提供了新见解。 急性暴露于高浓度 ...
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