a trimeric G-protein complex (Gα, Gβ, Gγ) and an effector. When activated, the receptor associates with the G-protein complex; this causes the exchange of GDP bound to Gα for GTP, followed by ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

These molecules are key players in health and disease. One such molecular switch is G protein-coupled receptor kinases, or GRKs for short. Their involvement in a broad range of diseases makes GRKs ...