that regulators of G-protein signalling (RGS) are likely to modulate the ratio of active to inactive G proteins rather than the time course of activation, and that the distribution of activated G ...

Cysteinyl leukotrienes (CysLTs) are potent bronchoconstrictors, playing pivotal roles in inflammatory diseases. These lipid ...

The data presented here demonstrate that the actions of ethanol on these channels are independent of G-protein activation and are not mediated by PKA or PKC or calcium ion influx, but this does ...

G Protein-Coupled Receptors (GPCRs) in advancing GPCR-targeted therapies, including the use of agonists, antagonists, biased ...

This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G ...

Adhesion G protein-coupled receptors (GPCRs ... The GAIN domain plays a central role in the activation of adhesion GPCRs.