Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components ...

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

One possibility is to block the activity of the effector molecules (e.g. cytokines) produced by the macrophages. An alternative approach is to block macrophage function by either altering the ...

Overall, this study uncovered a fascinating aspect of immune function: macrophages not only recognize bacterial threats but ...

Cardiac macrophages in newborn mice promoted heart cell proliferation after injury, offering a potential approach to regenerate cardiac tissue in adults.

Macrophages are critical for this process, directing tissue repair through the function of peroxisomes, which reduce inflammation and promote tissue regeneration by digesting lipids and toxins.

He plans to better understand how the activation status of macrophages couples with the transport function. “One of the ways to potentially approach this is to collect information from smaller length ...