Historically, flutamide's 'frontdoor' entry to the scene of antiandrogen therapy in women was closed in the 1990s, because of its rare but potentially severe hepatotoxicity when given in doses ...

Background: Flutamide has been rarely used for the treatment of female pattern hair loss (FPHL). Flutamide treatment for FPHL has not been evaluated in long-term studies with sufficiently large ...

It is peculiar that the employment of a potent antiandrogen, such as flutamide, in FPHL has been so underutilized. Recently, Scheinfeld [28] observed that flutamide is not in common use by ...