[21] Fibrin begins to build up on the catheter soon after insertion, sometimes developing into a sheath that may completely encase the catheter. In this case, infusions still may be possible ...

The matrix of absorbed protein, adherent leukocytes, aggregated platelets, and accumulated fibrin composes a "conditioning layer" that envelops the catheter as a fibrinous sheath. A partial or ...

Thrombin mediates fibrin polymerization and is known to be involved in acute and chronic inflammatory processes in vivo. Flick et al. have used various genetically engineered mouse models to study ...