【导读】雌激素受体阳性（ER+）乳腺癌约占病例的 70%。靶向雌激素的内分泌疗法是 ER+ 乳腺癌的一线疗法。然而，约有一半的患者会对这些疗法产生耐药性，从而导致生存率降低。

This may hint at what lies ahead as we navigate the (mostly erroneous) tendency to identify every cell death process in drug hepatotoxicity and other liver diseases as ferroptosis. DILI is broadly ...

A recent Nature Communications study identifies ferroptosis as a major cell death mechanism underlying COVID-19 lung disease. Study: Fatal COVID-19 pulmonary disease involves ferroptosis.

was present in a range of contexts where ferroptosis was occurring, including in aging brains and Huntington disease-affected ...

Alzheimer's disease could be slowed by aerobic exercise ... "Iron overload in the oligodendrocytes is an inducer of ferroptosis in aged brains," the researchers wrote. The researchers found ...

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

Aerobic exercise significantly lowers Alzheimer’s disease markers and improves brain health, offering a promising preventive strategy. Researchers plan human trials to validate these findings and ...

Glaucoma is a complex and multifactorial neurodegenerative disorder primarily characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual ...