Physiological extracellular matrix (ECM) calcification or mineralization is restricted to bones, teeth and the hypertrophic zone of growth plate cartilage. In contrast, pathological ECM ...

A comprehensive proteomic map of liver fibrosis progression and healing in two mouse models identifies etiology-specific extracellular matrix components, laying the foundation for targeted ...

Background Development of diffuse-type gastric cancer (DGC) starts with intramucosal lesions that are primarily composed of ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Scientists at CNIC have identified a specialized group of neutrophils in the skin that produce extracellular matrix. This ...

The work is published in the journal Nature Methods. The extracellular matrix supports and gives structure to our cells and tissues: It provides a scaffold for cells to grow in, dictates the ...

The joint meeting is an annual opportunity to showcase advances in extracellular matrix biology. Dr. Khoja commented, “Fibroblasts are a critical component of the extracellular matrix with ...

The joint meeting is an annual opportunity to showcase advances in extracellular matrix biology. Dr. Khoja commented, “Fibroblasts are a critical component of the extracellular matrix with ...

A new study has identified the protein ADAMTS5 as playing a crucial role in the spread of ovarian cancer cells, offering a ...

This study uses multimodal imaging—including SHG, SIMS, and TEM—to reveal how fibroblasts interact with 3D collagen scaffolds ...