Selecting an appropriate mouse model is one of the most important decisions a pre-clinical researcher can make. Which is best suited for immuno-oncology? Cancer research and drug discovery has ...

The mouse's current appeal as a model for human disease has its origins in the historical selection and breeding initiatives used for producing offspring with specific traits. Numerous mutants ...

“The MOP will be expanding into functional annotation of mouse genome with South Korean patients’ genes,” says Seong, “and we hope to combine our data with the Korean Animal Model Archive ...

the mouse has become the model of choice. Here the authors re-examine the value of this mouse model as a tool for understanding human diabetes and for testing potential therapies, reviewing both ...

In a mouse model, a single dose of ATL-201 durably suppressed seizures and improved behavior through six months, according to the firm.

A recent theory about the basis for fragile X syndrome is now validated in a mouse model. The findings point ... mGluR5 signaling for the treatment of epilepsy and FXS, and these compounds will ...

Atalanta Therapeutics, a biotechnology company pioneering RNA interference (RNAi) for the treatment of neurological diseases, today announced the publication of preclinical data in the journal ...

Researchers have found that an FDA-approved arthritis drug suppresses seizures and improves memory, offering new hope for a ...

Hoffman and Roopra have also filed for a patent on the use of the drug in epilepsy. More information: Olivia R. Hoffman et al, Disease modification upon 2 weeks of tofacitinib treatment in a mouse ...

The disease is characterized by symptoms such as epilepsy, developmental delay ... we created an innovative model using mouse neurons that mimics the disease caused by the TIMM50 protein mutation.

epilepsy, and schizophrenia. "GL-II-73 demonstrated an incredible ability to restore cognitive function in a mouse model of Alzheimer's, particularly when administered early in the disease," added Dr.