Ubiquitin and other ubiquitin-like molecules (UBLs) are post-translationally attached to proteins through a sequential enzymatic cascade that uses an E1 activating enzyme, an E2 conjugating enzyme ...

Next, they used the enzyme-cascade reaction method to detect glucose, which is a common biological molecule. In both cases their system showed decent analytic sensitivity, and they were able to ...

Cascade has long been a leading brand in dishwasher detergent, trying to fight off stuck-on food, grease, and spotty dishes—all while easing customers’ minds about the simplicity and effectiveness of ...

However, in a new breakthrough, published in the journal Nature Synthesis, the researchers have demonstrated how a "biocatalytic cascade"—a sequence of enzyme-driven reactions—can simplify the ...

In the case of the enzyme, isocitrate dehydrogenase ... In chemotaxis, the aspartate receptor becomes an inhibitor of the kinase cascade. The aspartate receptor is also induced into becoming ...

The CRISPR-Cascade assay achieves attomolar sensitivity ... Optimizations in reaction temperature (33°C), steric hindrance strategies, and enzyme kinetics improved specificity and reduced ...